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Consistent with the non-glycaemic effects of glucagon to inhibit food intake, enhance lipid metabolism and accelerate energy expenditure [70], a single-molecule GLP-1/GCGR co-agonist improved body weight and glucose control in mice with DIO beyond that observed with GLP-1 receptor agonism alone [114, 115]
These changes can be implemented immediately and can be an easy fix to potentially prevent these side effects, said Wajahath
No data beyond 5 years for any GLP-1/GIP agonist Potential for tolerance
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