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Documentation: Ensure comprehensive documentation is available, including Certificates of Analysis (CoA), Safety Data Sheets (SDS), and LCMS reports

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5 Hypoglycemic drugs, ferroptosis, and DCM 5.1 Metformin As a classic hypoglycemic drug, metformin has been previously found to be protective in DCM by alleviating apoptosis (88), improving autophagy, inhibiting pyroptosis (89), and alleviating fibrosis (90)

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Studies on -synuclein demonstrate that methionine residues near the N-terminus are more susceptible to copper-mediated oxidation than internal residues, with Met1 substitution decreasing Cu-peptide reduction potential by approximately 80 mV

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