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No significant changes in other weight-related biochemical markers were observed

[9] Because NNMT acts inside cells, an effective inhibitor has to get into cells throughout the body which is exactly why absorption and route matter, and why the membrane-permeability finding was highlighted in the first place

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The weight management criterion consisted of a body mass index (BMI) of 30 or higher or a BMI of 27 or above if the adults also had conditions such as hypertension, hyperlipidemia, or a history of stroke or myocardial infarctions