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Additionally, it has been reported that OS affects epigenetic regulatory mechanisms involved in the regulation of pancreatic cell survival and insulin secretion, like DNA methylation, chromatin architectural modification, and non-coding RNA (Kowluru and Mishra, 2017)
Seahorse assay Oxygen consumption rate was measured using a Seahorse Bioscience XF96 analyzer with an XF Cell Mito stress test kit (Agilent, 103015-100)
ratio: 54.2% vs
10.3389/fneur.2018.00873 60
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