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GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells
Blood sugar stabilization Chronically elevated blood sugar, even at levels that do not meet the diagnostic threshold for diabetes, causes persistent low-grade fatigue
Such high micromolar GSSG concentrations are unlikely to occur in most subcellular compartments but could be reached in the secretory pathway or during titration experiments of transgenic cell lines with an upregulated GSSG transporter 35,63,64,77
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