GSTP1 is generally not expressed in human hepatocytes (Sison-Young et al., 2015), however, expression is often up-regulated under stress conditions and in tumors (Tew and Townsend, 2012)
173 At the molecular level, gene modulation techniques, including siRNA- and shRNA-mediated silencing of efflux transporter genes (e.g., ABCB1, ABCG2), as well as CRISPR/Cas9-based gene editing, have successfully resensitized tumor cells to chemotherapy in preclinical models
The soya-and-oat blended drinks, called Alpro Meal To Go, contain 20g of protein and debuted in Germany this year, with a rollout expected in Switzerland and Austria shortly
Cell 187 , 16661684.e1626 (2024)