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The A1C reduction compared to placebo was similar to that of the SURPASS trial in adults with type 2 diabetes
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By engaging an additional hormonal pathway, Mounjaro appears to have a stronger impact on how the body handles glucose and stores energy
Particularly, liraglutide attenuates pre-established atherosclerosis throughout the aorta and aortic root in ApoE -/- mice via increasing macrophage polarization into anti-inflammatory macrophages and by reducing the number of pro-inflammatory macrophages [92]
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