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A 2026 UK review of the histamine-and-wakefulness science, the hippocampal-prefrontal evidence, the anticholinergic-burden & dementia question, why non-drowsy antihistamines come first and why treating the allergy, not a peptide, comes first Read the full review Autoimmune & Cognitive Neuroscience 23 June 2026 Dihexa for Sjgrens Syndrome Brain Fog: Sjgrens Fog, the Ianalumab NEPTUNUS Phase 3, Nipocalimab DAHLIAS & the 2026 UK Review My eyes and mouth are dry but its the fog thats wrecking my life. Up to 500,000 people in the UK live with Sjgrens the second most common autoimmune rheumatic disease after rheumatoid arthritis and brain fog and fatigue routinely rank above dryness for what disrupts daily life, with measurable cognitive impairment in ~4450%

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In compliance with the recommendations for public health, anyone with a cough, fever, loss of taste/or smell, flu-like symptoms

For example, one experiment in rabbits suggested that DSIP may help reduce electrical instability of the heart in emotional stress and mitigate stress-related events such as extrasystoles [7]