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Kidney failure, also called end-stage renal disease (ESRD), is the last stage of chronic kidney disease
One thing to consider is that because ME/CFS is a severely disabling disease, many patients are house or bedbound and are unable to visit the clinics multiple times for follow-up analyses (39), even though these very severe cases are estimated to be around 25% of the ME/CFS cases (11, 39, 587)
the proportion 1: 0.25 has only a negligible effect while the effect is more marked for the proportion 1: 0.5
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