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People over 50 are most at risk because your gut absorbs less B12 as you age
2016 Feb;101(2):533-8
However, the intranasal route of drug delivery still has some unresolved issues, such as the need to overcome cilia and mucosal clearance in the vestibular region, as well as enzymatic degradation after the introduction of nanotherapeutic formulations into the nasal cavity[166]
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