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This does not usually stop other medicines from working, but your clinician may review your medications or adjust how they are taken to make sure treatment remains safe and effective
It works by mimicking a hormone called GLP-1 (glucagon-like peptide-1) that targets areas of the brain responsible for appetite and food intake
This is particularly noteworthy because two competing oral small-molecule GLP-1 programs from Pfizer, lotiglipron (discontinued in 2023) and danuglipron (discontinued in April 2025), were terminated due to liver toxicity concerns
He had been filling his prescription at a local brick-and-mortar compounding pharmacy but turned to Zappy to buy a stockpile
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