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(1999) conducted a dose-escalation PK/PD study in healthy male volunteers (eight subjects per dose level) using five intravenous infusion rates (4.21140.45 nmol/kg over 15 minutes)

This phenomenon, known as "early worsening," is thought to result from rapid reduction in blood glucose levels rather than a direct drug effect

The early effects of intravenous L-propionyl carnitine on ulcerative trophic lesions of the lower limbs in arteriopathic patients: a controlled randomized study

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