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The findings obtained from the SMART collaborative meta-analysis (SGLT2 Inhibitor Meta-Analysis Cardio-Renal Trialists), designed to evaluate the impact of SGLT2is on cardiovascular and renal outcomes based on the concomitant use or non-use of GLP1-RAs, included 12 controlled clinical trials with 73,238 participants, of whom 3065 (4.2%) received GLP1-RAs

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