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Animal models of myocardial infarction show that TB-500 administration improves left ventricular function, reduces infarct size and cardiomyocyte death during ischemic events, and enhances cardiac microvascular density to improve tissue perfusion

With this condition, patients may also experience metabolic abnormalities, including dyslipidemia and cardiovascular disease

However, TB-500 also has some angiogenic properties, so the distinction may be one of degree rather than kind

The combination uses therapeutic but conservative doses of each component, and the synergistic effects actually allow for lower individual peptide amounts than if using them separately