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The apoptosis involved in SIMI encompasses the activation or inhibition of multiple pathways, including TNF- and MAPK-related, PI3K/AKT/mTOR, and NF-B signaling pathways, with the release of various inflammatory factors that directly lead to myocardial damage, resulting in increased secretion of inducible NO synthase and excessive production of NO (98,104)

Cancer 50 , 24492455 (2014)

This study is, to the best of the authors knowledge, the first systematic integration of FA metabolic derangements with GA pathogenesis and therapeutic development

For short term storage, peptides should be kept in their lyophilized (dry powder) form at 4C in a refrigerator