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J., Adam, K
That makes the combination easy to understand clinically, even while the final product remains investigational
However, the rate at which this can occur is limited and at higher exercise intensities is insufficient in matching the increased rate of hydrogen ion production, resulting in progressive acidification particularly of the strength-generating fast-twitch muscle fibers
For example, in particulate matter exposure-related models, GLS1-mediated enhancement of glutaminolysis, together with alterations in local Gln/-KG levels, can be accompanied by enhanced M1-like polarization, and inhibition of GLS1 can alleviate this pro-inflammatory polarization trend (60)
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