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IDO1, indoleamine 2, 3-dioxygenase 1

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Dysaesthesia has been reported in some clinical trials of semaglutide, including the STEP UP T2D trial of subcutaneous semaglutide, results of which showed that the adverse effect was more common with 7.2 mg doses (n=58 [18.9%] of 307) compared with 2.4 mg doses (n=five [4.9%] of 103)

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