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La inhibicin de la NNMT se ha asociado con una mayor disponibilidad de nicotinamida adenina dinucletido (NAD), un cofactor esencial en el metabolismo celular, lo que puede influir en la actividad mitocondrial y favorecer los procesos de sealizacin dependientes del NAD, incluida la activacin de la sirtuina-1 (SIRT1)
Additional NMR data are included in the Source Data file
Two compounds to source, two batches to verify
These properties have positioned it as a valuable tool in studies examining oxidative stress responses and inflammation-related signalling at the cellular level
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