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Potential drug interactions with berberine include: Blood thinners like clopidogrel (Plavix) Cyclosporine (Neoral, Sandimmune) and tacrolimus (Prograf), drugs used to prevent organ rejection Dextromethorphan (Robitussin DM), a cough suppressant Diabetes drugs such as metformin (Glucophage) Losartan (Cozaar), a blood pressure drug Sedatives like zolpidem (Ambien) and pentobarbital (Nembutal) Because berberine acts on the liver, it could cause interactions with other medications processed by this organ
Most cognitive supplements or medications work at the level of neurotransmitter modulation they increase dopamine, acetylcholine, or serotonin availability
doi: 10.1002/ptr.6647
Multiple investigational compounds for NAFLD treatment, including modulators of bile acid and lipid metabolism, are in phase II and phase III randomized controlled trials
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