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Astrup, et al.66, utilizaron la liraglutida para el tratamiento de la obesidad en 564 sujetos con ndice de masa corporal entre 30 y 40kg/m2, los cuales fueron asignados al azar a tres brazos: la liraglutida (cuatro dosis 1,2, 1,8, 2,8, 3mg), el orlistat o el placebo y los tres grupos recibieron una dieta con moderada restriccin calrica
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