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The degree of melanin pigmentation is determined by the number and distribution of melanocytes in the basal cell layer of the oral epithelium of each anatomical region, by their melanogenic activity, by the degree of arborisation of the dendritic processes of the melanocytes, and by the number, size, and distribution of melanosomes in the melanocyte-keratinocyte unit [46]
Who Is Excluded: Critical Clarifications This is where patients and prescribers must be particularly careful
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This metabolic foundation helps explain many of the broader effects discussed earlier
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