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By imitating the effects of GLP-1, semaglutide can: Reduce your appetite and reduce food noise Slow how long it takes for food to leave the stomach (increasing how long you feel full) Increase insulin secretion when blood sugar levels are high Overall, this encourages you to eat less
Estos frmacos incluyen semaglutida (Ozempic, Wegovy, Rybelsus), dulaglutida (Trulicity), liraglutida (Victoza, Saxenda), entre otros
By reducing excess weight, treatment may significantly lessen sleep apnoea severity, with studies showing improvement rates of up to 63% in some individuals
Such effects are consistent with their established reduction in atherosclerotic cardiovascular events and may be particularly relevant in patients with obesity, insulin resistance, or HFpEF phenotypes, and taken together, these mechanistic differences provide a biologically plausible rationale for combination therapy: SGLT2 inhibitors primarily target HF-related hemodynamic and cardiorenal pathways, whereas GLP-1 receptor agonists may further improve metabolic and vascular risk
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