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Development Note: Cagrilintide is currently in Phase 3 clinical trials (REDEFINE program) and has not yet received regulatory approval
doi: 10.1097/CEJ.0000000000000194 369
As mentioned, many of the studies looking at weight loss and berberine have included study participants who were already making other dietary and lifestyle changes known to support weight loss
However, delivering miRNAs or inhibitors specifically to beta cells remains a major hurdle for the clinical application of this therapeutic approach [29]
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