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Autophagy-associated proteins, including ATG2A, ATG5, ATG7, ATG9A, ATG14, and Beclin1, exhibit increased expression levels in response to hypoxic conditions, thereby facilitating the induction of autophagy in cancer cells [99,100,101,102,103]

This dose provided more weight loss but at the cost of significantly more adverse events

Furthermore, glutathionylated residue C151 of roGFP2 reacted three to four times faster than glutathionylated residue C208, which is again the opposed reactivity as observed for the oxidation kinetics of both monothiol roGFP2 variants (Table 1)

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