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Based on clinical trial data, retatrutide produces greater average weight loss (28.7% at 68 weeks with 12mg) compared to tirzepatide (22.5% at 72 weeks with 15mg)

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Orphanet: The portal for rare diseases and orphan drugs

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Postgraduate medicine 121 , 4658, doi:10.3810/pgm.2009.01.1954 (2009)

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Taking smaller bites, slowing down during meals, and avoiding high fat foods early in treatment can help minimize discomfort

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