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Sources: Tirzepatide Once Weekly for the Treatment of Obesity | New England Journal of Medicine Realworld use and effectiveness of tirzepatide among individuals without type 2 diabetes: Results from the Optum Market Clarity database PMC Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity | Obesity | JAMA Internal Medicine | JAMA Network Semaglutide StatPearls NCBI Bookshelf Safety of Semaglutide PMC Semaglutide, a glucagon like peptide-1 receptor agonist with cardiovascular benefits for management of type 2 diabetes PMC Realworld evidence on the utilization, clinical and comparative effectiveness, and adverse effects of newer GLP1RAbased weightloss therapies PMC Liraglutide for weight management: a critical review of the evidence PMC Liraglutide and not lifestyle intervention reduces soluble CD163 after comparable weight loss in obese participants with prediabetes or type 2 diabetes mellitus PMC Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial | Clinical Pharmacy and Pharmacology | JAMA | JAMA Network

Beyond weight loss and diabetes management, recent studies suggest GLP-1 drugs may offer other health benefits, too from treating addiction to lowering the risk of dementia

You may have heard of semaglutide under the brand names Ozempic, Rybelsus, Zepbound, and Wegovy

The most common sites for B12 injections are the deltoid (upper arm), vastus lateralis (outer thigh), ventrogluteal (hip), abdomen, and outer upper arm for subcutaneous injections