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To test whether the incretin hormone GLP-1 was the predominant contributor to the observed improvement of glucose homeostasis, we employed exendin 939 (Ex-9), a GLP-1 receptor antagonist
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Weight regain typically begins within the first few weeks and can continue for up to 18 months
A este fenmeno se le conoce como agonismo sesgado, y puede visualizarse en la comparacin esquemtica presentada en la Figura 2
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