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DA is also involved in the PD pathogenesis associated with genetic factors, including SNCA (encoding -synuclein [-syn]), LRRK2 (leucine-rich repeat kinase 2), PINK1 (PTEN-induced kinase 1), Parkin , DJ-1 and GBA1 (glucocerebrosidase-1 [GCase]), contributing to DA neuronal degeneration [15,16,17,18,19]
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Glutathione crosses the blood-brain barrier in its liposomal form, where it protects neurons from free radical accumulation and supports mitochondrial function
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