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T2DM patients show significantly reduced IFN-:IL-4 ratios, confirming a measurable shift away from protective Th1 immunity
But in many ways, as you know Bret, history repeats itself
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Consistent with this model, NRF2 activation promotes transcription of genes involved in redox homeostasis and glutathione biosynthesis, including Gclc and Gclm (41, 63)
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