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Molecules, 25(3), 609
Virus protein ligands, like trimeric spike glycoprotein interact with cellular receptors, such as ACE2, and host proteases, like transmembrane protease serine 2 (TMPRSS2), participate in virus entry by proteolytically activating virus ligands (Sallenave and Guillot, 2020
Individuals with digestive conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or those recovering from gastrointestinal surgery may also benefit, since IV therapy bypasses the digestive tract and delivers nutrients directly to where theyre needed
Consequently, it is essential to investigate the mechanisms underlying immune escape, extraction, and targeted delivery [159]
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