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Moreover, an East-Asian MR study (N = 11,506) reported a probable causal effect of T2DM on MDD [62]
Participants in the oral semaglutide arm underwent a dose-escalation schedule (3 mg daily for 4 weeks, followed by 7 mg daily for 4 weeks, then 14 mg daily for the remainder of the trial) to minimize gastrointestinal side effects
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