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This tolerability gap may shrink with the optimized titration schedules being tested in Phase 3, but it represents a real limitation of the current Phase 2 protocol
53-62, pubmed.ncbi.nlm.nih.gov/15001067
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Signaling Cascade Upon GLP-1R Activation In vitro activation of GLP-1R by Acetyl GLP-1 MAX leads to: Increased intracellular cAMP levels via adenylate cyclase (AC) activation
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