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Stimulates bone collagen synthesis: BPC-157 directly promotes collagen production by fibroblasts, accelerating repair of soft tissues, ligaments, and tendons
Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome
Pramlintide (approved 2005): three-amino-acid substitution enabling solubility, 2-3 daily dosing before meals, approximately 23% weight loss in T2D
10.1016/j.bbagen.2012.09.008 92 MagtanongL.KoP
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