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Is the 2 mg Ozempic dose worth the upgrade from 1 mg
It boosts the development of bacteria that generate short-chain fatty acids (SCFAs) in the gut of people with T2DM, leading to an increase in SCFAs levels in the colon, ultimately improving host metabolism (Forslund et al., 2015
If you reach 8 mg and the side effects are making daily life difficult, dropping back to 4 mg and reassessing is not failure
In their respective Phase 3 obesity trials tirzepatide reached roughly 2022.5% and semaglutide 2.4 mg about 14.9%, compared with retatrutides 28.3% at 12 mg though these are separate trials and not head-to-head
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