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In rare cases, these side effects can be severe, and for some, this may outweigh the potential benefits of the treatment
10.1111/acel.13469 Aging Cell
Both UroA and spermidine increase the activity of SIRT1, and thus the expression and function of LC3, while inhibiting mTOR activity
An example week at the 2.5 mg initiation step: The documented protocol allows the injection day to be moved if needed as long as doses stay at least several days apart, but for research clarity a fixed weekday is cleanest
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