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An Iranian pilot study (2010, n=35) compared 600 mg silymarin daily with 30 mg fluoxetine over 8 weeks

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It is also worth noting that in 2024, the European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) and the MHRA reviewed available evidence and concluded that there is no causal link between GLP-1 receptor agonists like semaglutide and suicidal thoughts or self-harm

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