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A systematic review and meta-analysis by Yao et al demonstrated that GLP-1 RAs were superior to placebo in reducing hemoglobin A1c (HbA1c) and fasting plasma glucose levels in patients with T2DM
Vascular Pharmacology , 113, 6475
Reddys Laboratories, and Glenmarkin India, along with Huadong Medicine, Benemae Pharmaceutical, Hangzhou Jiuyuan Gene Engineering, and Innovent Biologics in China, are actively developing biosimilar and modified GLP-1 analogues targeting both domestic and global markets
Limited research is available regarding its safety during pregnancy, and unnecessary treatment may pose health risks for both the mother and the baby
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