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Promote resolution of acute inflammation (shifting from pro-inflammatory to pro-repair signals) while reducing chronic pathological inflammation
Its primary function is as a powerful antioxidant and detoxifying agent
Thus, B-12 deficiency may impair methionine synthesis from the methylation cycle
Indeed, the thermolabile MTHFR defect and heterozygosity for CBS deficiency might increase vascular disease risk by respectively increasing the amounts of dietary folate and vitamin B 6 that are needed to prevent hyperhomocysteinemia
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