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In addition, semaglutide did not affect maximum plasma concentration of concomitant medications to a relevant degree

Serious but rare side effects include pancreatitis (severe abdominal pain radiating to the back), gallbladder problems (upper right abdominal pain, especially after eating), kidney problems (usually related to severe dehydration), severe allergic reactions (difficulty breathing, severe rash, facial swelling), and vision changes (particularly in people with diabetes)