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Dual GLP-1/GIP agonists, such as tirzepatide, primarily enhance glycemic control and insulin sensitivity through synergistic incretin and -cell effects, producing the most pronounced HbA1c reductions among all classes
This common adverse effect occurs because Wegovy slows gastric emptying and acts on areas of the brain involved in nausea perception
This isnt anecdotal its a regulatory conclusion based on clinical trial data
The 5 mg dose of tirzepatide has been shown in studies to produce weight loss comparable to maximum-dose semaglutide , with the added benefit of GIP receptor activation
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