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The sedating effects are cumulative and can persist for 8-12 hours after dosing, making driving or operating machinery dangerous during initial treatment phases
Research in this area remains limited but emerging evidence provides some guidance
Testing varying concentrations of FCS in the assay medium revealed a right-shift in the semaglutide dose response curves with increasing FCS concentration, consequently resulting in a drop in the EC50 with decreasing concentration of FBS in the assay medium ( The concentration of drug used for stimulating the cells was also reevaluated
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