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Muscle loss is a significant practical concern, with studies showing that 30-40% of weight lost on GLP-1 agonists can be lean mass if protein intake and resistance training are neglected

The most frequently reported side effects include gastrointestinal symptoms such as nausea, diarrhoea, vomiting, constipation, and abdominal pain , which affect a significant proportion of patients, particularly during dose escalation

Monitoring helps identify low or high readings early, particularly during dose increases or when other diabetes medicines are used at the same time

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