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The clinical trials demonstrate that the vast majority of participants eventually achieve significant appetite suppression, but the timeline to get there varies by several weeks between individuals
PLoS Med (2004) 1(1):e27.10.1371/journal.pmed.0010027 5 HotamisligilGS
You must discuss all your current medications with your prescriber, as bupropion inhibits the enzyme CYP2D6 and may increase levels of other drugs metabolised by this pathway
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