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Due to the increased size of acidic vesicles, we stably expressed the ratiometric biosensor mTFP1-LAMP1-mCherry (FIRE-pHLy 36 ) based on luminal proton-quenchable TFP1 and cytosolic-facing mCherry to assess lysosomal pH (Figs
Nearly 90% of adults achieved an HbA1c of less than 7% with combination cagrilintide and semaglutide
Yaakoub et al
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