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A novel gastric pentadecapeptide bpc 157 with different beneficial activities and anticonvulsant effect interacting with gabaergic system could improve diazepam efficacy coadministered (10 microg/kg, 10 ng/kg i.p.) with diazepam (5.0 mg/kg i.p.) twice daily for 10 days, since diazepam chronic medication would otherwise predispose for diazepam- tolerance/withdrawal development (shorter latency to convulsion after convulsant)
Bannai S, Tateishi N
Food chemistry , 233 , 429-433
This doesnt necessarily mean the compound is unsafemany natural substances used for centuries lack extensive clinical trialsbut it does mean were working with incomplete data regarding human-specific effects, optimal dosing, long-term safety, and potential interactions
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