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Indeed GLP1 enhances the survival of SHSY5Y cells under glutamate- or ROS-induced stress, and it increases the activity of cyclic adenosine monophosphate(cAMP), protein kinase A (PKA), and AMP- activated protein kinase (AMPK)
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However, its equally important to be aware of potential side effects, such as stomach discomfort, nausea, and reduced vitamin B12 levels with long-term use
This is why Retatrutide is often discussed as a next-generation weight loss medication
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