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Our proposed clinical dose of BPC157 was 200 g/person/day, and its equivalent dose in rats was 20 g/kg (converted based on body surface area)
However, comparative studies suggest that Liproxstatin-1 may exhibit superior metabolic stability and a longer plasma half-life, potentially translating to a broader therapeutic window than Ferrostatin-1 in vivo (Skouta, 2014
This review consolidates the pivotal role of ferroptosis in exacerbating ischemic stroke pathology, driven by iron dysregulation, lipid peroxidation, and mitochondrial collapse
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