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Some researchers posit that this effect occurs via an intrinsic mechanism, while others hypothesize that it may be mediated through the paracrine actions of insulin or somatostatin

WO2010046357 and WO2009034119 disclose polypeptides comprising amylin analogs with albumin binding residues (referred to as amylin derivatives)

Obes Rev 24(7):e13568 Jensen SBK et al (2024) Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

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