First-time T2D diagnoses within 15 days of the first-time GLP-1 prescription increased with increasing obesity classes between 2020 and 2024 (Class 1: +19.7%, Class 2: +25.9%, Class 3: + 43.7%)

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4 Retatrutide has none of these yet, and the realistic UK approval window is late 2027 to mid 2028, with NHS access from 2029 at the earliest
The Role of the Kidneys and Natriuresis Beyond the brain, GLP-1 medications have a direct effect on your kidneys