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A recent data science evidence-based approach to determine the top ten ingredients in oral skin supplements (from 71,000 dietary ingredients of which 1781 were found to have at least one skin-related publication assessed in human clinical trials) found that collagen had the most published human skin health-related data, followed by specific antioxidants (especially from natural sources or products) [25]
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HDAC6 inhibitor Ricoliostat: HDAC6 inhibitors can promote the degradation of protein aggregates or protect neurons from oxidative stress, hence can be used as possible drugs for treating peripheral neuropathy
131 Although GLP-1Rs are present, they are limited in number, making the direct inhibitory effect of GLP-1 on -cells relatively weak
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